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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC7
All Species:
12.12
Human Site:
S504
Identified Species:
29.63
UniProt:
Q8N3Z6
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N3Z6
NP_115602.2
543
63052
S504
R
S
S
H
Y
H
T
S
R
E
D
K
S
P
K
Chimpanzee
Pan troglodytes
XP_001169534
543
63034
S504
R
S
S
H
Y
H
T
S
R
E
D
K
S
P
K
Rhesus Macaque
Macaca mulatta
XP_001114863
543
63168
S504
R
S
S
H
Y
H
M
S
R
E
D
K
S
P
K
Dog
Lupus familis
XP_538733
544
63251
P504
H
S
S
H
S
H
K
P
R
E
D
K
L
P
R
Cat
Felis silvestris
Mouse
Mus musculus
B1AX39
541
62982
L498
H
A
S
H
Y
H
R
L
R
E
E
R
L
L
R
Rat
Rattus norvegicus
B1WC15
542
63308
L499
Q
A
S
H
Y
H
R
L
R
E
E
K
L
R
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509565
566
65060
S524
H
L
A
C
Q
K
L
S
R
R
E
H
P
E
E
Chicken
Gallus gallus
XP_424418
619
69362
Q576
G
S
K
K
E
H
G
Q
Q
L
L
E
A
A
K
Frog
Xenopus laevis
A1L2T6
563
64391
K522
G
S
F
L
H
L
D
K
T
K
D
M
F
K
N
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001199064
921
104738
S724
K
E
V
T
A
L
M
S
K
E
Q
K
N
A
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
96.3
73.5
N.A.
64.8
64.8
N.A.
54.5
36.5
40.5
N.A.
N.A.
N.A.
N.A.
N.A.
22.1
Protein Similarity:
100
99.6
97.6
82.1
N.A.
77.1
76.9
N.A.
69.7
52
56.1
N.A.
N.A.
N.A.
N.A.
N.A.
34.6
P-Site Identity:
100
100
93.3
60
N.A.
40
46.6
N.A.
13.3
20
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
93.3
66.6
N.A.
66.6
73.3
N.A.
33.3
40
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
10
0
10
0
0
0
0
0
0
0
10
20
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
50
0
0
0
0
% D
% Glu:
0
10
0
0
10
0
0
0
0
70
30
10
0
10
10
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
20
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% G
% His:
30
0
0
60
10
70
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% I
% Lys:
10
0
10
10
0
10
10
10
10
10
0
60
0
10
40
% K
% Leu:
0
10
0
10
0
20
10
20
0
10
10
0
30
10
0
% L
% Met:
0
0
0
0
0
0
20
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
10
% N
% Pro:
0
0
0
0
0
0
0
10
0
0
0
0
10
40
0
% P
% Gln:
10
0
0
0
10
0
0
10
10
0
10
0
0
0
0
% Q
% Arg:
30
0
0
0
0
0
20
0
70
10
0
10
0
10
30
% R
% Ser:
0
60
60
0
10
0
0
50
0
0
0
0
30
0
0
% S
% Thr:
0
0
0
10
0
0
20
0
10
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
50
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _